AChR M5 Antibody ELISA

The AChR M5 Antibody ELISA is For Research Use Only

Sensitivity: Cut-off
Dynamic Range: 2.5 – 40 U/ml
Incubation Time: 3.5 hours
Sample Type: Serum
Sample Size: 100 µL
Alternative Name: Anti-Muscarinic Cholinergic Receptor (AChR) 5 (M5) Antibody ELISA Assay Kit
Controls Included

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REAGENTS: Preparation and Storage
This test kit must be stored at 2 – 8 °C upon receipt. For the expiration date of the kit refer to the label on the kit box. All components are stable until this expiration date. Prior to use allow all reagents to come to room temperature. If crystals have formed, mix gently until the crystals have completely dissolved. Reagents from different kit lot numbers should not be combined or interchanged.

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Assay Principle

The Eagle Biosciences muscarinic cholinergic receptor 5 (M5) ELISA assay kit is an antibody screening test. M5 receptor has been pre-coated onto a microtiter plate. During the first incubation the anti-muscarinic cholinergic recetor 5-antibodies of the samples are immobilized on the plate. The autoantibodies are detected with an HRP labeled anti-human IgG antibody. In the following enzymatic substrate reaction, the intensity of the colour correlates with the concentration and/or avidity of anti-muscarinic cholinergic receptor 5 antibodies.

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EagleBio的5α-雄甾烷-3α，17β-二醇葡糖醛酸化物是C19类固醇，缩写为3α-DiolG，5α二醇G或简称为α二醇G。它主要作为睾丸激素和二氢睾丸激素（DHT）的代谢产物生产。它主要在目标外围组织（例如皮肤）中产生，尤其是在毛囊周围。大量的3α-DiolG刺激会导致过多的头发形成，特别是在女性通常不存在头发的地方。近年来，在研究患有特发性多毛症的妇女的临床研究人员中，人们对这种类固醇的测量越来越感兴趣。已知是3α-DiolG前体的类固醇包括脱氢表雄酮（DHEA），硫酸脱氢表雄酮（DHEAS），二氢睾丸酮（DHT），雄烯二酮和睾丸激素。已显示只有3α-DiolG随多毛症增加而随治疗减少。这种相关性在多囊卵巢综合征（PCO）患者中也得到了证明。3α-DiolG的测定因此被证明是多种方式的有用指标，包括监测特发性多毛症和PCO妇女的治疗进展。此外，接受环孢霉素A治疗的糖尿病患者（无论男女）均显示3α-DiolG水平升高，这种副作用导致以前无毛的区域出现了头发。3α-DiolG的测定因此被证明是多种方式的有用指标，包括监测特发性多毛症和PCO妇女的治疗进展。此外，接受环孢霉素A治疗的糖尿病患者（无论男女）均显示3α-DiolG水平升高，这种副作用导致以前无毛的区域出现了头发。3α-DiolG的测定因此被证明是多种方式的有用指标，包括监测特发性多毛症和PCO妇女的治疗进展。此外，接受环孢霉素A治疗的糖尿病患者（无论男女）均显示3α-DiolG水平升高，这种副作用导致以前无毛的区域出现了头发。