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FCGRT antibody {FITC}
Catalog Number: orb156854-FITC
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DatasheetProduct Overview
| Product Name | FCGRT antibody {FITC} |
|---|---|
| Catalog Number | orb156854-FITC |
| Species/Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Canine, Sheep |
| Conjugation | FITC |
| Tested applications | ICC, IF |
| Immunogen | KLH conjugated synthetic peptide derived from the region aa61-140 of human FCGRT |
| Target | FCGRT |
| Alternative Names | (click to expand) |
Product Properties
| Form/Appearance | Liquid: PBS(pH7.4) |
|---|---|
| Concentration | - 100 μg (in 522 μl): 0.19 mg/ml |
| Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Purity | Affinity purified by Protein A |
| MW | 37 kDa |
| Uniprot ID | P55899 (Human) |
| Entrez | 2217 |
Product Description
Rabbit polyclonal antibody to FCGRT, which is also known as FCRN and neonatal Fc receptor. FCRN is a protein frequently found in the Single-pass type I membrane and is expressed in the uterus as well as hematopoietic bone marrow. It is overexpressed in spleen and nasopharynx. It extensively binds to the Fc region of monomeric immunoglobulins gamma i.e. IgG. IgG in milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids.
Application Notes
| Dilution Range | ICC: 1:100-500, IF: 1:100-500 |
|---|
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Biorbyt的mCherry。在cds质粒转染的293HEK细胞中，通过Western blot检测到一条29 kDa的条带。该抗体可很好地识别tdTomato，不识别GFP（绿色荧光蛋白）。
