Isotype: Mouse IgG1k

Immunogen: Recombinant human CD269

INFORMATION : Human CD269 (BCMA, B cell maturation antigen) is predominantly expressed by mature B cells and is a type I TNF superfamily receptor member (TNFRSF17) . It is highly specific for its ligand CD257 (BAFF, Blys).

Antibody ANC3B1 binds to recombinant CD269 (but not CD268) in EIA and native CD269 expressed on Raji cell surface. It blocks binding of recombinant soluble CD257(BAFF)trn-muCD8(cat# 525-020) to recombinant CD269(BCMA)-muIg (cat# 519-020) in EIA.

REFERENCES: 1) Schneider P., J. Tschopp, et al. J. Exp. Med. 1999, 189(11):1747-1756.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。