Human CD34 is an unusual glycosylated membrane protein exclusively expressed on immature hematopoietic cells and on endothelial cells. CD34 may have a role in cell adhesion. CD34 has extensive utility for bone marrow transplantation (3, 4).

Isotype: Murine IgG3 kappa

Immunogen: Human KG-1a tumor cells

Specificity: Antibody 43A1 recognizes the class II epitope of the 110 kd CD34 molecule (1, 2,) which is resistant to neuraminidase and sensitive to glycoprotease (6).

References:

1. H.J. Bühring, et al, (1991) Leukemia 5: 854-860.

2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 840-874.

3. R.H. Collins, (1994) Stem Cells 12: 577-585.

4. T.L. Holyoake & M.J. Alcorn, (1994) Blood Reviews 8: 113-124.

5. J.P. Levesque, L.J. Bendell, et al. (2003) J Clin Invest 110: 187-196.

6. Lanza R, Sutherland DR, et al. (2001) J Biol Regulators and Homeostatic Agents 15:1-13.

7. M Vigano, de Girolamo, et al. (Feb 2017) J Exp Orthopaedics 4: 8.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。