Human CD86 (B7-2) is a costimulating ligand for CD28 and CTLA-4. CD86 is expressed on activated B cells and blood monocytes (3).

Isotype: Murine IgG1

Immunogen: ARH-77 (B-lymphoblastoid cell line)

Specificity: Antibody BU63 recognizes the CD86 molecule of 80 kd (3).

Functional Application: Antibody BU63 blocks MLR and blocks binding of soluble CD152-muIg fusion protein to CD86.

References:

1. C. Caux, et al, (1994) J Exp Med 180: 1841-1847.

2. C.B. Thompson, (1995) Cell 81: 979-982.

3. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 703-705.

4. D. Mauri, et al, (1995) J Immunol 155: 118-127.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。