The human CD1 genetic locus consists of five closely related genes (1). Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, a subset of B cells, and on most professional antigen presenting cells (2). CD1a⁺/CD11c⁺ dendritic cells are direct precursors of Langerhans cells in peripheral blood (4). CD1 molecules have a specialized lipid antigen-presenting function (3)..

Isotype: Murine IgG1kappa

Immunogen: Human Jurkat tumor cells

Specificity:Antibody CB-T6 recognizes the CD1a molecule of about 49 kd.

References:

1. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 33-37.

2.Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 337-341.

3. E.M. Beckman, et al, (1994) Nature 372: 691-694.

4.T. Ito, et al, (1999) J Immunol 163: 1409-1419.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。