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Isotype: Rat IgM
Immunogen: RAW112 cells
INFORMATION: Antibody RA3-3A1 binds to an extracellular epitope of B220 (CD45R), the 220 kD variant of the T200, CD45 molecule present on B cells and B cell precursors. CD45R is implicated in a signaling pathway that involves motility and dendrite formation (2).
References:
1) Coffman RL, Weissman IL. (1981) Nature 289(5799): 681-683.
2) Partida-Sanchez S, Santos-Argumedo L, et al. (2000) Eur J Immunol 30(9): 2722-2728.
Ancell防鼠CD45R(B220)纯化(含抗生素)同种型: 大鼠IgM免疫原: RAW112细胞信息:抗体RA3-3A1与B220(CD45R)的胞外表位结合,B220是T200的220 kD变异体,存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径(2)。