Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells in the immune system. It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and viruses. Antibody ERIC-1 recognizes a stem region epitope of the CD56 molecule(4).
Isotype: Murine IgG1 kappa
Immunogen: Human retinoblastoma tumor tissue, membrane fraction (1)
Specificity: Antibody ERIC-1 recognizes the CD56 molecule found on NK cells.
References:
1) S.P. Bourne, et al, (1991) J Neuro-Oncol 10: 111-119.
2) T.L. Whiteside and R.B. Herberman, (1994) Clinical & Diagnostic Laboratory Immunology 1: 125-133.
3) H. Spits, et al, (1995) Blood 85: 2654-2670.
4) R. Gerardy-Schahn, M Eckhardt, (1994) Int J Cancer: Supp 8: 38-42.
Ancell防鼠CD45R(B220)纯化(含抗生素)同种型: 大鼠IgM免疫原: RAW112细胞信息:抗体RA3-3A1与B220(CD45R)的胞外表位结合,B220是T200的220 kD变异体,存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径(2)。