Isotype: Mouse IgG1k

Immunogen: Recombinant human TIGIT

INFORMATION: Human TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a co inhibitory receptor expressed by activated T cells, memory T cells, Treg cells and NK cells. It binds ot CD155(PVR) and less avidly to CD112(PVRL2).

Specificity: Antibody ANCTG6 binds to receptors on a sub set of human peripheral blood lymphoid cells, as well as to recombinant TIGIT in EIA.

References: 1) Dougall WC, AC Anderson, et al. (2017) Immunol Rev 276(1): 112-120. doi: 10.1111/imr.12518 PMID: 28258695

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。