Human CD26 is a T cell activation antigen which can be associated with costimulation (1). The significance of the dipeptidyl peptidase IV activity remains unknown. Characterization of adenosine deaminase binding to CD26 suggests an important immunoregulatory role (2). Soluble CD26 serum levels are predictive for colorectal cancer (3). CD26 is expressed at high levels on CD4+ Th17 T cells (4).

Isotype: Murine IgG2b

Immunogen: Human T cell clone

Specificity: Antibody 202.36 reacts with the type II membrane protein CD26.

References:

1.) Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995) p. 1105-1114.

2.) R.P. Dong, et al, (1996) J Immunol 156: 1349-1355.

3.) OJ Cordero, M Páez de la Cadena, et al, (2000) British Journal of Cancer 83(9), 1139–1146.

4.) Bengsch B, R Thimme, et al, (2012) J Immunol 188(11): 5438-5447.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。