Human CD29 is the beta subunit of an integrin family of molecules expressed on diverse cell types which function as the major receptors for extracellular matrix and as cell-cell adhesion molecules. CD29 can form heterodimer pairs with at least nine different alpha subunits (1).
Isotype: Murine IgG1kappa
Immunogen: Human ocular melanoma cell line, V+B2
Specificity: Antibody 4B7R recognizes the CD29 integrin subunit. It has been reported to work in Western blot under non reducing conditions at a concentration of 1-2 μg/ml. It has also been reported to cross react with Porcine and Mouse CD29.
References:
1. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1612-1613.
2. C M Michelo, I Joosten, et al. (2016) Transplant Immunology 37: 1-9. PMID: 27142560
3. O Trubiani, G Ramazotti, et al. (2016) Cell Signal 28(11): 1631-1641 PMID: 27478064
Ancell防鼠CD45R(B220)纯化(含抗生素)同种型: 大鼠IgM免疫原: RAW112细胞信息:抗体RA3-3A1与B220(CD45R)的胞外表位结合,B220是T200的220 kD变异体,存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径(2)。