Human CD270 (Herpes Virus Entry Mediator, HVEM, TNFRSF14, ATAR, LIGHTR, TR2 ) is a 36kd type I membrane protein that has been found on a broad range of lymphoid tissues. Its ligands include the TNF Ligand family members LTalpha and LIGHT, and the CD28/Ig Superfamily member BTLA(2).

Molecular Structure: A soluble fusion protein consisting of the extracellular (187aa) domain of mature human HVEM fused to murine IgG2a Fc (233aa) with a predicted non glycosylated molecular weight of 46.4 kd.

Transfectant Cell Line: CHO

Functional Application: Human CD270-muIg fusion protein binds to recombinant BTLA and LIGHT in EIA (3).

References:

1) Hsu H, et al. (1997) J Biol Chem 272:13471.

2) Gonzalez LC, et al. (2005) PNAS 102(4): 1116-1121.

3) Guifang Cai, Gordon J Freeman, et al. (2008) Nature Immunol 9: 176 - 185.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。