Human CD56 is an adhesion molecule from the Ig superfamily which is restricted to NK cells in the immune system. It is believed that NK cells form a first line of defense against tumor cells and cells infected with bacteria and viruses.

Molecular Structure: A soluble fusion protein consisting of the extracellular loop domains 1-4 (370aa) of human CD56 (20)LQVDIV….CTASN(389)

fused to murine IgG2a Fc and hinge (232aa), with a predicted monomeric molecular weight of kd 67.8.

Transfectant Cell Line: CHO

Functional Application: CD56(trn)-muIg fusion protein blocks binding of anti-human CD56 antibody (cat #308-020, but not cat #208-020) to NK cells present in ficoll prepared human PBL.

References:

S.P. Bourne, et al, (1991) J Neuro-Oncol 10: 111-119. T.L. Whiteside and R.B. Herberman (1994) Clinical & Diagnostic Laboratory Immunology. H. Spits, et al, (1995) Blood 85: 2654-2670.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。