Human CD48 (SLAMF2) is a GPI anchored cell surface gylcoprotein found on all lymphocytes and monocytes. CD48 is a ligand for CD2 as well as CD229 and CD244(2B4, SLAMF4), and may be involved in enhancing the activating signal to B cells.

Isotype: Murine IgG2a

Immunogen: Human PBLs

Specificity: Clone 5-4.8 recognizes epitope 4 of the CD48 molecule of about 47 kd (4). This mAb blocks binding of biotinylated recombinant CD244(2B4,SLAMF4)-muIg (Cat# 544-030) to CD48 in FACS.

References:

1. H.A. Vaughan, et al, (1983) Transplantation 36: 446-450.

2. H.A. Vaughan, et al, (1991) Immunogenetics 33: 113-117.

3. E.N. Klyushnenkova, et al, (1996) Cellular Immunol 174: 90-98.

4. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 509-512.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。