The cytokine human interferon-gamma (IFN-gamma) is a glycosylated protein that exists as a homodimer of 34 kd in its biologically active form. IFN-gamma is expressed upon activation by TH1 cells CD8⁺ cells and NK cells (2). Secreted IFN-gamma is a potent inhibitor of in vitro hematopoiesis and appears to serve as an important regulator of lymphocyte and macrophage function by exerting antiproliferative effects (1). Antibody ANC2E11 binds to recombinant and cellular IFN-gamma in EIA and Flow cytometry.

Isotype: Murine IgG1 kappa

Immunogen: Recombinant human IFN-gamma

References:

1. H.A. Young & K.J. Hardy (1995) J Leuk Biol 58: 373-381.

2. A. Bilkiau (1996) Adv Immunol 62: 61-130.

3. T. Sato, et al (1997) Blood 90: 4749-4758.

Ancell防鼠CD45R（B220）纯化（含抗生素）同种型：  大鼠IgM免疫原：   RAW112细胞信息：抗体RA3-3A1与B220（CD45R）的胞外表位结合，B220是T200的220 kD变异体，存在于B细胞和B细胞前体上。CD45R参与了涉及运动性和枝晶形成的信号传导途径（2）。