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商品描述
| Product Name | Transdermal PeptideACSSSPSKHCG |
| Size | 1 mg |
| Catalog # | AS-62066 |
| US$ | $63 |
This short synthetic peptide facilitates efficient transdermal protein drug delivery through intact skin. Co-administration of the peptide and insulin to the abdominal skin of diabetic rats results in elevated systemic levels of insulin and suppresses serum glucose levels. This peptide creates a transient opening in the skin barrier to enable macromolecular drugs to reach systemic circulation. | |
| Detailed Information | |
| Storage | -20°C |
| References | Chen, Y. et al. Nat. Biotechnol. 24, 455 (2006). |
| Molecular Weight | 1063.2 |
| ACSSSPSKHCG | |
| Sequence(Three-Letter Code) | H - Ala - Cys - Ser - Ser - Ser - Pro - Ser - Lys - His - Cys - Gly - OH |
| Product Citations | Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J doi:10.1042/BJ20101021. |


