Product Name | Transdermal PeptideACSSSPSKHCG |
Size | 1 mg |
Catalog # | AS-62066 |
US$ | $63 |
This short synthetic peptide facilitates efficient transdermal protein drug delivery through intact skin. Co-administration of the peptide and insulin to the abdominal skin of diabetic rats results in elevated systemic levels of insulin and suppresses serum glucose levels. This peptide creates a transient opening in the skin barrier to enable macromolecular drugs to reach systemic circulation. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Chen, Y. et al. Nat. Biotechnol. 24, 455 (2006). |
Molecular Weight | 1063.2 |
ACSSSPSKHCG | |
Sequence(Three-Letter Code) | H - Ala - Cys - Ser - Ser - Ser - Pro - Ser - Lys - His - Cys - Gly - OH |
Product Citations | Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J doi:10.1042/BJ20101021. |