品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
| Product Name | IKKγ NEMO Binding Domain (NBD) Inhibitory PeptideDRQIKIWFQNRRMKWKKTALDWSWLQTE |
| Size | 1 mg |
| Catalog # | AS-61169 |
| US$ | $181 |
| Purity | % Peak Area By HPLC ≥ 95% |
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ref: Paria, B. et al. J. Biol. Chem. 278, 37195 (2003); Tian, M. et al. Blood May 2005(10.1182/blood-2004-04-1248); Bharti, A. Blood 101, 1053 (2003). |
| Molecular Weight | 3693.3 |
| DRQIKIWFQNRRMKWKKTALDWSWLQTE | |
| Sequence(Three-Letter Code) | H - Asp - Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Thr - Ala - Leu - Asp - Trp - Ser - Trp - Leu - Gln - Thr - Glu - OH |
