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商品描述
| Product Name | Amylin (1 - 37), humanKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (Disulfide bridge: 2 - 7) |
| Size | 1 mg |
| Catalog # | AS-60804 |
| US$ | $318 |
| Purity | % Peak Area By HPLC ≥ 95% |
This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ref: Jhamandas, J. et al. J. Neurophysiol. 89, 2923 (2003). |
| Molecular Weight | 3904.5 |
| KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (Disulfide bridge: 2-7) | |
| Sequence(Three-Letter Code) | H - Lys - Cys - Asn - Thr - Ala - Thr - Cys - Ala - Thr - Gln - Arg - Leu - Ala - Asn - Phe - Leu - Val - His - Ser - Ser - Asn - Asn - Phe - Gly - Ala - Ile - Leu - Ser - Ser - Thr - Asn - Val - Gly - Ser - Asn - Thr - Tyr - OH (Disulfide bridge: 2 - 7) |
| Product Citations | Pilkington, EH. Et al. (2017). Effects of Protein Corona on IAPP Amyloid Aggregation, Fibril Remodelling, and Cytotoxicity. Sci Rep 7(1):2455. doi: 10.1038/s41598-017-02597-0.Wang, M. et al. (2017). Differential effects of silver and iron oxide nanoparticles on IAPP amyloid aggregation. Biomater Sci. 5(3):485-493. doi: 10.1039/c6bm00764c.Su, L. et al. (2017). The effect of aluminum ion on the aggregation of human islet amyloid polypeptide (11-28). Acta Biochim Biophys Sin (Shanghai). 49(4):355-360. doi:10.1093/abbs/gmx015Ly, H. et al. (2017). Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia. Ann Neurol. doi:10.1002/ana.24992. |
