Product Name | Orexin B, human |
Size | 1 mg |
Catalog # | AS-65573 |
US$ | $263 |
Purity | Peak Area by HPLC ≥95% |
Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control. | |
Detailed Information | DatasheetMaterial Safety Data Sheets (MSDS) |
Storage | 20°C |
References | 1. Martynska L., et.al., Neuroendocr Lett 4(26), 289-292 (2005).2. Ebrahim I.O., et.al., J of Royl Soc of Med95, 227-230 (2002).3. Ramanjaneya M., et.al., Endocrinology151 (7), 3169-3180 (2010). |
Molecular Weight | 2898.9 |
RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2 | |
Sequence(Three-Letter Code) | Arg - Ser - Gly - Pro - Pro - Gly - Leu - Gln - Gly - Arg - Leu - Gln - Arg - Leu - Leu - Gln - Ala - Ser - Gly - Asn - His - Ala - Ala - Gly - Ile - Leu - Thr - Met - NH2 |