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商品描述
| Product Name | Cathepsin D and E FRET SubstrateMca - GKPILFFRLK(Dnp) - r - NH2 |
| Size | 1 mg |
| Catalog # | AS-61793 |
| US$ | $147 |
| Purity | % Peak Area By HPLC ≥ 95% |
An internally quenched fluorogenic substrate (Ab/Em =328/393 nm) for cathepsins D and E and not for B, H or L, obtained from the hepatopancreas (liver) of the Japanese common squid (Todarodes pacificus). The cleavage occurs at the Phe-Phe amide bond resulting in enhanced fluorescence and is used in screening cathepsin D and E inhibitors and for determining cathepsin D and E activity in tissue cell extracts. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Yasuda, Y. et al. J. Biochem. 125, 1137 (1999). |
| Molecular Weight | 1756.1 |
| Mca-GKPILFFRLK(Dnp)-r-NH2 | |
| Sequence(Three-Letter Code) | 7 - Methoxycoumarin - 4 - Acetyl - Gly - Lys - Pro - Ile - Leu - Phe - Phe - Arg - Leu - Lys(Dnp) - D - Arg - NH2 |
