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商品描述
| Product Name | HIF - 1 {alpha} (556 - 574)DLDLEMLAPYIPMDDDFQL |
| Size | 1 mg |
| Catalog # | AS-61528 |
| US$ | $131 |
| Purity | % Peak Area By HPLC ≥ 95% |
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in response to a lack of oxygen. This part of HIF-1binds to the von Hippel-Lindau factor (VHL) an E3 ubiquitin ligase, and the proline 564 is absolutely critical to the binding process | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ref: Hirsilä, M. et al. J Biol. Chem278, 30772 (2003); Robinson, B. Pediatric Research 50, 673 (2001). |
| Molecular Weight | 2254.6 |
| DLDLEMLAPYIPMDDDFQL | |
| Sequence(Three-Letter Code) | H - Asp - Leu - Asp - Leu - Glu - Met - Leu - Ala - Pro - Tyr - Ile - Pro - Met - Asp - Asp - Asp - Phe - Gln - Leu - OH |
