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商品描述
| Product Name | Exendin (5 - 39)TFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS - NH2 |
| Size | 1 mg |
| Catalog # | AS-63898 |
| US$ | $249 |
| Purity | % Peak Area By HPLC ≥ 95% |
This truncated Exendin-4 peptide, Exendin (5-39) amide, is a potent Glucagon-Like Peptide 1 (GLP-1) receptor antagonist. Unlike the full length Exendin-4 (a GLP-1 agonist), Exendin (5-39) antagonizes GLP-1stimulated insulin release after food intake. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Montrose-Rafizadeh, C. et al. J Biol Chem 272, 21201 (1997)Eng, J. et al. J Biol Chem 267, 7402 (1992)Greig, NH. et al. Diabetolog 42, 45 (1999)Göke R. et al. J Biol Chem 268, 19650 (1993) |
| Molecular Weight | 3806.3 |
| TFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 | |
| Sequence(Three-Letter Code) | H - Thr - Phe - Thr - Ser - Asp - Leu - Ser - Lys - Gln - Met - Glu - Glu - Glu - Ala - Val - Arg - Leu - Phe - Ile - Glu - Trp - Leu - Lys - Asn - Gly - Gly - Pro - Ser - Ser - Gly - Ala - Pro - Pro - Pro - Ser - NH2 |
