Product Name | Syntide - 2 [PLARTLSVAGLPGKK]PLARTLSVAGLPGKK |
Size | 5 mg |
Catalog # | AS-22552 |
US$ | $209 |
Purity | % Peak Area By HPLC ≥ 95% |
The native peptide, PLARTLSVAGLPGKK (cat# 22511), is a selective substrate for CaM kinase II and protein kinase C. It is a poor substrate for phosphorylase kinase and is not phosphorylated by myosin light chain kinase. The sequence of PLARTLSVAGLPGKK is homologous to phosphorylation site 2 in glycogen synthase. The relative Vmax/Km ratios of the peptide for different kinases are 100 for CaMK II, 22 for protein kinase C, 2 for phosphorylase kinase, and 0.5 for myosin light chain kinase respectively. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Ref: Kumar KA. and Babu PP. Neurosci. Lett. 336, 121 (2003); Inoue S. et al. Biochem. Biophys. Res. Commun. 215, 861 (1995); Hashimoto, Y. and TR. Soderling, Arch. Biochem. Biophys. 252, 418 (1987). |
Molecular Weight | 1507.9 |
PLARTLSVAGLPGKK | |
Sequence(Three-Letter Code) | H - Pro - Leu - Ala - Arg - Thr - Leu - Ser - Val - Ala - Gly - Leu - Pro - Gly - Lys - Lys - OH |
Product Citations | Harrison, BC. et al. Mol Cel Biol. 26, 3875 (2007).Sonoda, H. et al. (2007). Requirement of Phospholipase D for Ilimaquinone-induced Golgi Membrane Fragmentation. J Biol Chem 282, 34085. |