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商品描述
| Product Name | Trp CageNLYIQWLKDGGPSSGRPPPS |
| Size | 1 mg |
| Catalog # | AS-62072 |
| US$ | $125 |
| Purity | % Peak Area By HPLC ≥ 95% |
This peptide is a C-terminal fragment of exendin-4. This 20-residue construct is over 95% folded in water at physiological pH, and exhibits a tightly folded tertiary structure in solution. Trp Cage is a highly stable mini-protein fold. It consists of a short helix, a 3,10 helix and a C-terminal poly-proline that packs against a Trp in the alpha helix. It is known to fold within 4 nanoseconds. This stable fast-folding Trp Cage sequence displays special stabilizing features specific to this miniprotein. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ding, F. et al. Biophys. J. 88, 147 (2005); Neidigh, J. et al. Nat. Struct. Biol. 9, 425 (2002); Adams, C. et al. J. Am. Soc. Mass. Spectrom. 15, 1087 (2004); Herman, R. et al. J. Biol. Chem. 282, 9813 (2007). |
| Molecular Weight | 2169.4 |
| NLYIQWLKDGGPSSGRPPPS | |
| Sequence(Three-Letter Code) | H - Asn - Leu - Tyr - Ile - Gln - Trp - Leu - Lys - Asp - Gly - Gly - Pro - Ser - Ser - Gly - Arg - Pro - Pro - Pro - Ser |
