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商品描述
| Product Name | Glucagon (1 - 29), bovine, human, porcineHSQGTFTSDYSKYLDSRRAQDFVQWLMNT |
| Size | 1 mg |
| Catalog # | AS-22457 |
| US$ | $131 |
| Purity | % Peak Area By HPLC ≥ 95% |
Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia. | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | O"Harte. FP. et. al.Mol Cell Endocrinol 381, 26 (2013), doi: 10.1016/j.mce.2013.07.014Drucker DJ. Endocrinology: Adult and Pediatric (7th Ed.) 1, 586 (2016), doi:10.1016/B978-0-323-18907-1.00034-2 |
| Molecular Weight | 3482.8 |
| HSQGTFTSDYSKYLDSRRAQDFVQWLMNT | |
| Sequence(Three-Letter Code) | H - His - Ser - Gln - Gly - Thr - Phe - Thr - Ser - Asp - Tyr - Ser - Lys - Tyr - Leu - Asp - Ser - Arg - Arg - Ala - Gln - Asp - Phe - Val - Gln - Trp - Leu - Met - Asn - Thr - OH |
