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商品描述
| Product Name | Fluorescein - 5 - maleimide |
| CAS | 75350-46-8 |
| Size | 25 mg |
| Catalog # | AS-81405 |
| US$ | $167 |
| Purity | ≥95% by HPLC |
Maleimides are among the most frequently used reagents for thiol modification.In most proteins, the site of reaction is at cysteine residues that either are intrinsically present or result from reduction of cystines. Unlike iodoacetamides, maleimides do not react with histidines and methionines under physiological conditions. Fluorescein-5-maleimide is one of the most popular fluorescent dyes for thiol modifications of proteins.
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| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C desiccated and protected from light |
| References | 1. Winograd E, et al. Mol Biochem Parasitol 136, 243-8; (2004).2. Van der Sluis EO, et al. FEBS Lett 527, 159-65; (2002). |
| Molecular Weight | 427.36 |
| Molecular Formula | C24H13 NO7 |
| Spectral Properties | Abs/Em = 493/515 nm |
| Solvent System | DMF or DMSO |
| Product Citations | Newbern, J. et al. (2007). c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons. Neurosci 147, 680.Kamaduri, H, er al. (2013). Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. elife2, e00828. doi: 10.7554/eLife.00828.Newbern, J. et al. (2007). c-Jun N-terminal kinase signaling regulates events associated with both health and degeneration in motoneurons. Neurosci 147, 680. |
