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商品描述
| Product Name | Biotin - LC - Angiotensin IIBiotin - LC - DRVYIHPF |
| Size | 5 mg |
| Catalog # | AS-60276-5 |
| US$ | $272 |
| Purity | % Peak Area By HPLC ≥ 95% |
This octapeptide Angiotensin II, DRVYIHPF, is biotinylated on the N-terminus via an LC (long chain, also known as 6-Aminohexanoyl, 6-Aminocaproyl or Ahx) linker. It can be used in ELISA assay. Angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It is also implicated in the regulation of cell proliferation, fibrosis and apoptosis. Ang II is formed by cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a chymotrypsin-like serine proteinase, hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | 1, Cobb, C. et al. Gen Comp Endocrinol 127, 8 (2002) 2, Lundequist, A. et al. J Biol Chem 279, 32339 (2004)3, Kinoshita, A. et al. J Biol Chem 266, 19192 (1991) 4, Spyroulias, G. et al. Eur J Biochem 270, 2163 (2003). |
| Molecular Weight | 1385.7 |
| Biotin-LC-DRVYIHPF | |
| Sequence(Three-Letter Code) | Biotin - LC - Asp - Arg - Val - Tyr - Ile - His - Pro - Phe - OH |
| Product Citations | Young, SH. & E. Rozengurt (2006). Qdot nanocrystal conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells. Am J Physiol-Cell Physiol 290, C728. doi: 10.1152/ajpcell.00310.2005. |
