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商品描述
| Product Name | Cetrorelix Acetate, Cetrotide |
| Size | 1 mg |
| Catalog # | AS-60869 |
| US$ | $186 |
| Purity | % Peak Area By HPLC ≥ 95% |
A highly modified luteinizing hormone-releasing hormone (LHRH) decapeptide with a terminal amide group, this peptide is a LHRH antagonist. It regulates the expression of Galphas and Galphai protein subunits and adenylate cyclase activity in ovary, breast and pituitary. Cetrorelix competitively inhibits LHRH receptor in the pituitary gland to suppress ovarian and testicular functions. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Ref: Collado, B. et al. Intl. J. Oncol. 24, 725 (2004); Schwahn, M. et al. Drug Metabolism and Disposition. 28, 10 (2000). |
| Molecular Weight | 1431.260 |
| Ac-{d-A[3-(2-naphthyl)]}-[d-F(4-Cl)]-{d-A[3-(3-pyridyl)]}-SY-(d-Cit)-LRP-d-A-NH2Acetate | |
| Sequence(Three-Letter Code) | Ac - {D - Ala[3 - (2 - naphthyl)]} - [D - Phe(4 - Cl)] - {D - Ala[3 - (3 - pyridyl)]} - Ser - Tyr - (D - Cit) - Leu - Arg - Pro - D - Ala - NH2 Acetate |
| Product Citations | Chou, C. et al.J. Clin. Endocrinol. Metab.88, 3806 (2003). |
