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商品描述
| Product Name | Tat - C (48 - 57)CGRKKRRQRRR |
| Size | 1 mg |
| Catalog # | AS-62063 |
| US$ | $68 |
This peptide is amino acids 48 to 57 fragment of TAT with an additional cysteine residue at the N-terminus. This peptide contains the protein transduction domain (PTD) of the HIV Tat protein that inhibits HSV-1 entry. The addition of a cysteine residue to the N-terminus of the Tat-PTD (Tat-C peptide) improves the antiviral activity against HSV-1 and HSV-2. Tat-C acts extracellularly, blocking entry of adsorbed virus immediately without eluting virions. | |
| Detailed Information | |
| Storage | -20°C |
| References | Bultmann, H. et al. Antimicrob. Agents Chemother. 51, 1596 (2007). |
| Molecular Weight | 1499.8 |
| CGRKKRRQRRR | |
| Sequence(Three-Letter Code) | H - Cys - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - OH |
| Product Citations | Xiong, X. et al. (2010). Virus-mimetic polymeric micelles for targeted siRNA delivery. Biomater 31, 5886. |


