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商品描述
| Product Name | Oxonol VI[Bis - (3 - propyl - 5 - oxoisoxazol - 4 - yl)pentamethine oxonol] |
| Size | 100 mg |
| Catalog # | AS-84704 |
| US$ | $164 |
Oxonol VI is used as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is a sensitive slow-response membrane potential probe whose magnitude of optical response is much larger than that of faster response probes (Oxonol V). The fluorescence of Oxonol VI decreases upon membrane hyperpolarization. In general, slow response probes are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.
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| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | -20°C desiccated and protected from light |
| References | 1. Cheng Z, et al. (2004).Am J Physiol Regul Integr Comp Physiol 286, R625-33.2. Koo YE, et al. (2004).Anal Chem 76, 2498-505. 3. Wu CC, et al. (2004).Cereb Cortex 14, 543-54.4. Suksaweang S, et al. (2004).Dev Biol 266, 109-22. 5. Iriyama A, et al. (2004). Invest Ophthalmol Vis Sci 45, 943-7. 6. Vest RS, et al. (2004).Biophys J 86, 2251-60.7. Zhang X and Kirsch LE (2004).Pharm Dev Technol 9, 219-27. 8. Hefnawy MA and Abou-Zeid AM (2003).Acta Microbiol Pol 52, 53-64.9. Jordan MB, et al. (2003).Blood 101, 594-601.10. Bianchi L, et al. (2003).J Biol Chem 278, 12415-24.11. deAzevedo LC, et al. (2003).J Neurobiol 55, 288-98.12. Ramani K and Balasubramanian SV (2003).Biochim Biophys Acta 1618, 67-78. |
| Molecular Weight | 316.352 |
| Molecular Formula | C17H20N2O4 |
| Spectral Properties | Abs/Em = 599/634 nm |
| Solvent System | DMSO |
| Product Citations | Mennerick, S. et al. (2010). Diverse Voltage-Sensitive Dyes Modulate GABAAReceptor Function. J Neurosci 30, 2871. |
