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商品描述
| Product Name | [Trp63, 64] - C3a (63 - 77)WWGKKYRASKLGLAR |
| Size | 1 mg |
| Catalog # | AS-61119 |
| US$ | $108 |
| Purity | % Peak Area By HPLC ≥ 95% |
This peptide, which is a C-terminal analogue of the complement factor C3a, acts as an agonist to the C3a receptor. It is derived from the fifteen C-terminal residues (6-77) of C3a. In in vitro studies, both C 3a and this peptide have been shown to selectively bind to C3aRs and induce degranulation of C3aR-transfeted RBL-2H3 cells. There was also a rapid, transient and concentration-dependent hypertensive response observed in rats when infused intravenously with C3a and this peptide. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | 1, Proctor LM et al. Intl Immunopharmacol. 9, 800-806 (2009). 2, Ames, R. et al. Immunopharmacol. 38, 87 (1997). |
| Molecular Weight | 1820.2 |
| WWGKKYRASKLGLAR | |
| Sequence(Three-Letter Code) | H - Trp - Trp - Gly - Lys - Lys - Tyr - Arg - Ala - Ser - Lys - Leu - Gly - Leu - Ala - Arg - OH |
| Product Citations | Russell, J. et al. (2011). Parallel detection of intrinsic fluorescence from peptides and proteins for quantification during mass spectrometric analysis Anal Chem 83 (6) 21872193. doi: 10.1021/ac103023q. |
