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商品描述
| Product Name | Bacterial Sortase Substrate III, Abz/DNPAbz - LPETG - K(Dnp) - NH2 |
| Size | 1 mg |
| Catalog # | AS-63717 |
| US$ | $244 |
| Purity | % Peak Area By HPLC ≥ 95% |
The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and colonization-associated surface proteins to the cell wall. SrtA selectively recognizes a C-terminal LPXTG motif. SrtA readily reacts with its native substrate Abz-LPETG-Dap(DNP)-NH2, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this FRET substrate can be monitored at Ex/Em=320 nm/420 nm. | |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C |
| References | Bentley, M. et al. J. Biol. Chem. 282, 6571 (2007). |
| Molecular Weight | 928.0 |
| Abz-LPETG-K(Dnp)-NH2 | |
| Sequence(Three-Letter Code) | Abz - Leu - Pro - Glu - Thr - Gly - Lys(Dnp) - NH2 |
