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蚂蚁淘在线 / 品牌中心 / Anaspec / Anaspec/SensoLyte ® Anti - alpha - Synuclein (Human) ELISA Kit/1 kit/AS-55550-H
商品描述
| Product Name | SensoLyte ® Anti - alpha - Synuclein (Human) ELISA Kit |
| Size | 1 kit |
| Catalog # | AS-55550-H |
| US$ | $546 |
This kit is optimized to detect human alpha-Synuclein (α-Synuclein) in cell and tissue lysate, and in human body fluids such as cerebrospinal fluid (CSF) and plasma. Wells are pre-coated with anti-α-Synuclein monoclonal antibodies, blocked, and stabilized for long-term storage. The amount of α-Synuclein is quantified using sandwich ELISA: rabbit polyclonal anti-α-Synuclein specific antibodies directly conjugated to horseradish peroxidase (HRP) are used to detect captured α-Synuclein.One Step Convenient Format o Pre-coated and pre-blocked 96-well strip plateo Ready-to-use substrate solution and other assay componentso One step assay (samples and detection antibody are added simultaneously)o 1 hour assay time at room temperature (excluding incubation time)Minimal Sample Size o Requires only 10-20 μl of cell and tissue lysate or body fluidsHigh Sensitivity o Detects 5 pg/ml of α-Synuclein (calculated as three standard deviations from the blank)Broad Dynamic Range o8-500 pg α-Synuclein/ml in the assayed sampleRELATED PRODUCTS: alpha-Synuclein Recombinant Proteins | |
| Detailed Information |  Datasheet Material Safety Data Sheets (MSDS) |
| Storage | 4°C |
| Product Citations | Tanriöver G, et al. (2020) Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions. Acta neuropathologica communications. 8(1):133. doi: 10.1186/s40478-020-00993-8.Oh SH, et al. (2017). The cleavage effect of mesenchymal stem cell and its derived matrix metalloproteinase-2 on extracellular α-synuclein aggregates in parkinsonian models. Stem cells translational medicine. 2017 6(3):949-61. doi:10.5966/sctm.2016-0111Vivacqua G, et al. (2016). Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson"s Disease. PLoS One. 11(3):e0151156. doi: 10.1371/journal.pone.0151156.Prusiner, B. S. (2015). Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism pnas 112 doi: 10.1073/pnas.1514475112.Woerman, A. L. (2015). Propagation of prions causing synucleinopathies in cultured cells. PNAS 112 doi: 10.1073/pnas.1513426112.Al-Nimer, MS. et al. (2014). Saliva α-synuclein and a high extinction coefficient protein: A novel approach in assessment biomarkers of Parkinson"s disease. North Am J Med Sci 6, 633. doi: 10.4103/1947-2714.147980.Maia, LF. et al. (2013). Changes in amyloid-β and tau in the cerebrospinal fluid of transgenic mice overexpressing amyloid precursor protein. Sci Transl Med 5, 194re2.Smith, LM. et al. (2012). α-Synuclein and anti-α-synuclein antibodies in Parkinsons disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls. PloS One 7, e52285. |
