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商品描述
| Product Name | delta PKC (8 - 17); PKC d InhibitorSFNSYELGSL |
| Size | 1 mg |
| Catalog # | AS-65111 |
| US$ | $68 |
| Purity | % Peak Area By HPLC ≥ 95% |
This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice. | |
| Detailed Information | |
| Storage | -20°C |
| References | Bright, R. et al. J Neurosci 24, 6880 (2004). Tanaka, M. et al. Circulation 110, 194 (2004). Braun, M and D. Mochly-Rosen. J Mol Cell Cardiol 35 895 (2003). Chen, L. et al. Proc Natl Acad Sci USA 98, 11114 (2001). |
| Molecular Weight | 1116.2 |
| SFNSYELGSL | |
| Sequence(Three-Letter Code) | H - Ser - Phe - Asn - Ser - Tyr - Glu - Leu - Gly - Ser - Leu - OH |


