Description

Product Name	JC - 1[5,5",6,6" - tetrachloro - 1,1",3,3" -tetraethylbenzimidazolylcarbocyanine iodide]
CAS	47729-63-5
Size	5 mg
Catalog #	AS-88060
US$	$180
Purity	≥95% by HPLC
Widely used for measuring membrane potential of mitochondria; 585/520 Fluorescence ratio increases upon cell hyper-polarization.
Detailed Information	Material Safety Data Sheets (MSDS)
Storage	-20°C desiccated and protected from light
References	1. Cheng Z, et al. (2004).Am J Physiol Regul Integr Comp Physiol 286, R625-33. 2. Koo YE, et al. (2004).Anal Chem 76, 2498-505. 3. Wu CC, et al. (2004).Cereb Cortex 14, 543-54. 4. Suksaweang S, et al. (2004).Dev Biol 266, 109-22. 5. Iriyama A, et al. (2004). Invest Ophthalmol Vis Sci 45, 943-7. 6. Vest RS, et al. (2004).Biophys J 86, 2251-60. 7. Zhang X and Kirsch LE (2004).Pharm Dev Technol 9, 219-27. 8. Hefnawy MA and Abou-Zeid AM (2003).Acta Microbiol Pol 52, 53-64. 9. Jordan MB, et al. (2003).Blood 101, 594-601. 10. Bianchi L, et al. (2003).J Biol Chem 278, 12415-24. 11. deAzevedo LC, et al. (2003).J Neurobiol 55, 288-98. 12. Ramani K and Balasubramanian SV (2003).Biochim Biophys Acta 1618, 67-78.
Molecular Weight	652.224
Molecular Formula	C25H27Cl4IN4
Spectral Properties	Abs/Em = 514/529 nm
Solvent System	DMSO
Product Citations	Rama, D. et al. (2011). Expression of chemokine-like receptor 1 (CMKLR1) on J744A. 1 macrophages co-cultured with fibroblast and/or tumor cells: modeling the influence of microenvironment. Cell immunol 271, 134. doi: 10.1016/j.cellimm.2011.06.016.Snyder, A. et al. (2010). HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. AIDS 24, 1107.

AnaSpec是一家由多肽合成、荧光标记、抗体、树脂合成专家团队组成的生物企业，为全世界的科研工作者提供全套的蛋白质组学研究解决方案。产品线主要分三个部分：多肽、检测试剂和树脂等化学试剂，适合基础研究、高通量筛选和药物发现等方面；还提供多肽合成、抗体生产和分析试剂盒开发。能合成不同数量级（mg-g级）的多种长度序列肽，常规合成肽为50个氨基酸或更长。2009年，美国Anaspec公司被Eurogentec收购