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商品描述
| Product Name | JC - 1[5,5",6,6" - tetrachloro - 1,1",3,3" -tetraethylbenzimidazolylcarbocyanine iodide] |
| CAS | 47729-63-5 |
| Size | 5 mg |
| Catalog # | AS-88060 |
| US$ | $180 |
| Purity | ≥95% by HPLC |
Widely used for measuring membrane potential of mitochondria; 585/520 Fluorescence ratio increases upon cell hyper-polarization.
| |
| Detailed Information |  Material Safety Data Sheets (MSDS) |
| Storage | -20°C desiccated and protected from light |
| References | 1. Cheng Z, et al. (2004).Am J Physiol Regul Integr Comp Physiol 286, R625-33.2. Koo YE, et al. (2004).Anal Chem 76, 2498-505. 3. Wu CC, et al. (2004).Cereb Cortex 14, 543-54.4. Suksaweang S, et al. (2004).Dev Biol 266, 109-22. 5. Iriyama A, et al. (2004). Invest Ophthalmol Vis Sci 45, 943-7. 6. Vest RS, et al. (2004).Biophys J 86, 2251-60.7. Zhang X and Kirsch LE (2004).Pharm Dev Technol 9, 219-27. 8. Hefnawy MA and Abou-Zeid AM (2003).Acta Microbiol Pol 52, 53-64.9. Jordan MB, et al. (2003).Blood 101, 594-601.10. Bianchi L, et al. (2003).J Biol Chem 278, 12415-24.11. deAzevedo LC, et al. (2003).J Neurobiol 55, 288-98.12. Ramani K and Balasubramanian SV (2003).Biochim Biophys Acta 1618, 67-78. |
| Molecular Weight | 652.224 |
| Molecular Formula | C25H27Cl4IN4 |
| Spectral Properties | Abs/Em = 514/529 nm |
| Solvent System | DMSO |
| Product Citations | Rama, D. et al. (2011). Expression of chemokine-like receptor 1 (CMKLR1) on J744A. 1 macrophages co-cultured with fibroblast and/or tumor cells: modeling the influence of microenvironment. Cell immunol 271, 134. doi: 10.1016/j.cellimm.2011.06.016.Snyder, A. et al. (2010). HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. AIDS 24, 1107. |
