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商品描述
Cat. No.: 218 111
Amount: 100 µg
Price:415.00€
| Cat.No.218111 | 100 µg purified IgG, lyophilized. Azide was added before lyophilization. For reconstitution add 100µlH2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C until use. |
| Applications | WB:1 : 500 up to 1 : 1000(see remarks) galleryIP:not tested yetICC:not tested yetIHC:1 : 500(see remarks) galleryIHC-P/FFPE:1 : 200 up to 1 : 500(see remarks) galleryELISA:yes ; unlabeled only(see remarks) gallery |
| Clone | NT78 |
| Subtype | IgG2b (κ light chain) |
| Immunogen | Synthetic peptide corresponding to AA 1 to 16 from human Abeta (UniProt Id: P05067) |
| Epitop | Epitop: AA 4 to 16 from human Abeta (UniProt Id: P05067) |
| Reactivity | Reacts with: human (P05067), mouse (P12023).Other species not tested yet. |
| Specificity | Specific for Abeta 38, 40, 42, 43. |
| Remarks | WB:Boil membrane after blotting for 3min.IHC:Antigen retrieval with formic acid is required.IHC-P:Antigen retrieval with formic acid is required.ELISA:Suitable as capture antibody for sandwich-ELISA with cat.no. 218011BT as detector antibody. |
| Data sheet | 218_111.pdf |
References for Abeta 38/40/42/43 - 218111
Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.JawharS, WirthsO, SchillingS, GraubnerS, DemuthHU, BayerTAThe Journal of biological chemistry (2011) 2866: 4454-60. 218111 IHC
Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis.WirthsO, ErckC, MartensH, HarmeierA, GeumannC, JawharS, KumarS, MulthaupG, WalterJ, IngelssonM, Degerman-GunnarssonM, et al.The Journal of biological chemistry (2010) 28553: 41517-24. 218111 ELISA
