Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, RatProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:RBMXL2Official Gene Full Name:RNA binding motif protein, X-linked-like 2NCBI Gene Id:27288Protein Name:RNA-binding motif protein, X-linked-like-2Swissprot Id:O75526Protein Accession #:NP_055284Nucleotide Accession #:NM_014469Alias Symbols:HNRNPG-T, HNRPGT, HNRNPGTReplacement Item:This antibody may replace item sc-101134 from Santa Cruz Biotechnology.Description of Target:The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 cProtein Size (# AA):392Molecular Weight:43kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express RBMXL2. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express RBMXL2. 
Immunogen:The immunogen is a synthetic peptide directed towards the middle region of human RBMXL2Predicted Homology Based on Immunogen Sequence:Cow: 85%; Dog: 77%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 77%; Rabbit: 85%; Rat: 85%Complete computational species homology data:Anti-RBMXL2 (ARP40773_P050)Peptide Sequence:Synthetic peptide located within the following region: SSRDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYGConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:UBC; RABGGTA; FDXACB1; CAND1; COPS5; CUL1; CUL3; CUL4B; SUMO1; DYRK2; TRA2B;Blocking Peptide:For anti-RBMXL2 (ARP40773_P050) antibody is Catalog # AAP40773 (Previous Catalog # AAPY01025)Datasheets/Manuals:Printable datasheet for anti-RBMXL2 (ARP40773_P050) antibodySample Type Confirmation:RBMXL2 is supported by BioGPS gene expression data to be expressed in HEK293T
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