TCS, a catheter lock solution, combines two active ingredients vital to the effective management of vascular access catheters; Taurolidine and Citrate. When TCS is instilled in device lumens, their internal flow passages are resistant to clot formation and hostile to bacterial and fungal growth. TCS is non-toxic and there are no known systemic effects. Taurolidine, an anti-microbial agent, promotes catheter patency by preventing Biofilm formation while Citrate, acts as the anticoagulant.
the taurolidine component offers broad spectrum antimicrobial activity against aerobic and anaerobic gram-positive and gram-negative bacteria, yeast and fungi interacts with the components of microbial cell walls, resulting in irreparable injury prevents biofilm development and consequently bacterial and fungal colonization, decreasing the risk of infection does not induce the development of resistant microbes.
the citrate component forms a complex with calcium, disrupting the normal coagulation cascade, precipitating it into an unusable form inhibiting blood coagulation with no systemic effect.
TCS is effective in the prevention of catheter associated infections and occlusions in all laboratory species from rodents to non-human primates. TCS has a favorable safety profile. It is non-toxic and has no known topical or systemic effect. No development of resistance to TCS has been reported.
Braintree的鼠标幻影-为Micro-CT扫描仪提供参考标准Micro-CT系统可提供精确，准确和高分辨率的测量结果。这些系统的视野要求适当缩放的QA体模。CIRS 090型MicroMouseTM和091型注水鼠标幻影提供了量化X射线衰减和吸收特性方面的钙和骨密度的工具。羟基磷灰石（HA）是哺乳动物牙齿和骨骼的主要成分，是评估矿物质密度的最合适参考。CIRS将HA与软组织等效的聚合物背景混合在一起，以提供参考值，其HA负荷范围为0 mg / cc至750 mg / cc。羟基磷灰石的晶粒尺寸和棒的均质性已优化，可用于Micro-CT。固态MicroMouse幻影和注水鼠标幻影均包含11种不同矿物含量和尺寸的棒。它们可以像评估全身扫描仪一样用于评估Micro-CT扫描仪。该目标适用于确定对比度的可检测性和估计低对比度的分辨率。在MicroMouse Phantom中，杆嵌入在软组织等效的环氧材料中，该材料的大小和形状均与小型啮齿动物相同。充满水的鼠标幻影在防水的聚碳酸酯外壳中包含11个杆，非常耐用并且耐多种化学物质。091型外壳可轻松填充各种液体，以改变杆和周围液体之间的对比度。090和091型中使用的11根Micro-CT棒也可以作为092型单独购买，以及其他长度，直径和HA装载选项。发送电子邮件以获取更多详细信息。特征：25 mg / cc-750 mg / cc HA目标肺，肌肉和脂肪适用于Micro-CT固体或液体填充
