Poly-D-Lysineis asynthetic amino acid chain that is positively charged and widely used as acoating to enhance cell attachment and adhesion to both plasticware andglass surfaces. This molecule is resistant to enzymatic degradation andhas been used to culture a wide variety of cell types.

The molecular weight ofPoly-D-Lysine can vary significantly with lower molecular weight (30,000 Da)being less viscous and higher molecular weight (>300,000 Da) having morebinding sites per molecule. This product’s molecular weight ranges from70,000 to 150,000 Da yielding a solution viscosity for easy handling whileproviding sufficient binding sites for cell attachment.

Poly-D-Lysinesurfacecoatings are designed to improve cell attachment, growth and differentiation ofmany cell types. Coated surfaces will often improve cell attachment inreduced or serum-free conditions.