Reconstitution and Storage:Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.Gene Symbol:PLK1Alias Symbols:PLK, STPK13NCBI Gene Id:5347Protein Name:Serine/threonine-protein kinase PLK1Description of Target:Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Swissprot Id:P53350Protein Accession #:NP_005021Nucleotide Accession #:BC014846Molecular Weight:49 Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express PLK1. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express PLK1. 
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
