PredictedSpeciesReactivity:Cow,Dog,GuineaPig,Human,Rabbit,Rat,SheepProductFormat:Liquid.100ulin10mMHEPES(pH7.5),150mMNaCl,100ugpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.Clonality:PolyclonalHost:RabbitApplication:WBAdditionalInformation:Packaging:100ulin10mMHEPES(pH7.5),150mMNaCl,100ugpermlBSAand50%glycerol.Adequateamountofmaterialtoconduct10-miniWesternBlots.ReconstitutionandStorage:Forlongtermstorage-20Cisrecommended.Stableat-20Cforatleast1year.GeneSymbol:DDCNCBIGeneId:1644ProteinName:Aromatic-L-amino-aciddecarboxylaseSwissprotId:P20711ProteinAccession#:NP_000781.1ReplacementItem:Thisantibodymayreplaceitemsc-293287fromSantaCruzBiotechnology.DescriptionofTarget:DOPAdecarboxylase(aromaticL-aminoaciddecarboxylase,AADC;DDC)catalyzesthesecondreactioninthebiosynthesisofcatecholaminesandSEROtonin(WaymireandHaycock,2002;Berryetal.,1996;Haycocketal.,2003).Itisalsoinvolvedinthebiosynthesisoftraceamines.DDCantibodiescanthereforebeusedasMarkersfordopaminergic,noradrenergicandserotonergicneuronsinavarietyofapplicationsincludingdepression,schizophrenia,Parkinson"sdiseaseanddrugabuse(Kishetal.,2001;Zhuetal.,2000;Zhuetal.,1999). MolecularWeight:~55kDaPurification:PreparedfromrabbitserumbyaffinitypurificationusinganAminOlinkPluscolumnmatrixtowhichpurified,recombinantbovineDDCwascoupled. TissueTool:FindtissuesandcelllinessupportedbyDNAarrayanalysistoexpressDDC.
RNASeq:FindtissuesandcelllinessupportedbyDNAarrayanalysistoexpressDDC.
Immunogen:PeptidefromN-terminusregionofhumanDOPAdecarboxylase(DDC),conjugatedtokeyholelimpethemocyanin(KLH).PredictedHomologyBasedonImmunogenSequence:Cow;Dog;GuineaPig;Human;Rabbit;Rat;SheepDatasheets/Manuals:PrintabledatasheetforOAPC00100Specificity:Specificforthe~55kDDCprotein. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
