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avivasysbio/Anti-Voltage Gated Potassium Channel, Kv2.2 Subunit (OAPC00001)/OAPC00001/100 ul

价格
¥6980.00
货号:OAPC00001-100ul
浏览量:73
品牌:avivasysbio
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商品描述
Gene Symbol:
KCNB2
NCBI Gene Id:
621349
Protein Name:
Potassium voltage-gated channel subfamily B member 2
Swissprot Id:
Q63099
Description of Target:
Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996).
Molecular Weight:
~100kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Prepared from rabbit serum by affinity purification using a Sulfo-Link column matrix to which the peptide immunogen was coupled.
Application:
WB, IHC
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KCNB2.
RNA Seq:
Find tissues and cell lines supported by DNA array analysis to express KCNB2.
Immunogen:
Peptide from the subunit region of the voltage gated potassium channel, Kv2.2 of rat and Xenopus, conjugated to keyhole limpet hemocyanin (KLH).
Predicted Species Reactivity:
Rat
Predicted Homology Based on Immunogen Sequence:
Rat
Product Format:
Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
Reconstitution and Storage:
For long term storage -20C is recommended. Stable at -20C for at least 1 year.
Datasheets/Manuals:
Printable datasheet for OAPC00001
Specificity:
Specific for the ~125k voltage gated potassium channel, Kv 2.2 subunit.
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。