Gene Symbol:KCNB2NCBI Gene Id:621349Protein Name:Potassium voltage-gated channel subfamily B member 2Swissprot Id:Q63099Description of Target:Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety of non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996).Molecular Weight:~100kDaHost:RabbitClonality:PolyclonalPurification:Prepared from rabbit serum by affinity purification using a Sulfo-Link column matrix to which the peptide immunogen was coupled.Application:WB, IHCTissue Tool:Find tissues and cell lines supported by DNA array analysis to express KCNB2. 
RNA Seq:Find tissues and cell lines supported by DNA array analysis to express KCNB2. 
Immunogen:Peptide from the subunit region of the voltage gated potassium channel, Kv2.2 of rat and Xenopus, conjugated to keyhole limpet hemocyanin (KLH).Predicted Species Reactivity:RatPredicted Homology Based on Immunogen Sequence:RatProduct Format:Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.Reconstitution and Storage:For long term storage -20C is recommended. Stable at -20C for at least 1 year.Datasheets/Manuals:Printable datasheet for OAPC00001Specificity:Specific for the ~125k voltage gated potassium channel, Kv 2.2 subunit. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。