Gene Symbol:SLC6A11NCBI Gene Id:79213Protein Name:Sodium- and chloride-dependent GABA transporter 3Swissprot Id:P31647Protein Accession #:NP_077348.1Description of Target:Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-3 has been found to be localized to astrocytes within the cerebral cortex indicating that this transporter mediates GABA uptake into glial cells (Minelli et al., 1996).Molecular Weight:~67kDaHost:RabbitClonality:PolyclonalPurification:Prepared from rabbit serum by affinity purification via chromatography with a column made with the peptide used as antigen.Application:WB, IHCTissue Tool:Find tissues and cell lines supported by DNA array analysis to express SLC6A11. 
RNA Seq:Find tissues and cell lines supported by DNA array analysis to express SLC6A11. 
Immunogen:Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-3.Predicted Species Reactivity:Mouse, RatPredicted Homology Based on Immunogen Sequence:Mouse; RatProduct Format:Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.Reconstitution and Storage:For long term storage -20C is recommended. Stable at -20C for at least 1 year.Datasheets/Manuals:Printable datasheet for OAPC00139Specificity:Specific for the ~67k GAT-3 protein. Immunolabeling is blocked by the peptide used as antigen. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
