Tested Species Reactivity:HumanPredicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:NR2C2Official Gene Full Name:Nuclear receptor subfamily 2, group C, member 2NCBI Gene Id:7182Protein Name:Nuclear receptor subfamily 2 group C member 2Swissprot Id:P49116Protein Accession #:NP_003289Nucleotide Accession #:NM_003298Alias Symbols:TAK1, TR2R1, TR4, hTAK1Replacement Item:This antibody may replace item sc-9086 from Santa Cruz Biotechnology.Description of Target:Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.Protein Size (# AA):615Molecular Weight:67kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express NR2C2. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express NR2C2. Immunogen:The immunogen is a synthetic peptide directed towards the N terminal region of human NR2C2Predicted Homology Based on Immunogen Sequence:Cow: 88%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%Complete computational species homology data:Anti-NR2C2 (ARP38288_P050)Peptide Sequence:Synthetic peptide located within the following region: FTSLNKEKIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVILConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:VPRBP; CUL4B; UBC; DDB1; KDM1A; NR2C2; HSP90AA1; JAZF1; TAB2; TRAF6; PELI1; PELI2; RBCK1; PDLIM7; TAB1; TRIM28; MTA1; HDAC3; NR2C1; RBBP4; HDAC1; DNMT1; CHD4; Cebpb; ITSN2; CD2AP; RXRB; NR2C2AP; PEBP1; HSP90AB1; CDC37; IKBKB; FKBP5; TRAF2; CHUK; HNF4A; ARBlocking Peptide:For anti-NR2C2 (ARP38288_P050) antibody is Catalog # AAP38288 (Previous Catalog # AAPP23127)Datasheets/Manuals:Printable datasheet for anti-NR2C2 (ARP38288_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。