Tested Species Reactivity:HumanPredicted Species Reactivity:HumanProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitApplication:WBReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:TUBA1AOfficial Gene Full Name:tubulin alpha 1aNCBI Gene Id:7846Protein Name:tubulin alpha-1A chainSwissprot Id:P68363Protein Accession #:NP_001257328.1Nucleotide Accession #:NM_001270399.1Alias Symbols:LIS3, TUBA3, B-ALPHA-1Description of Target:Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Protein Size (# AA):451Molecular Weight:50 kDaPurification:Affinity purifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express TUBA1A. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express TUBA1A. 
Immunogen:The immunogen is a synthetic peptide directed towards the C terminal region of human TUBA1APeptide Sequence:Synthetic peptide located within the following region: AKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlBlocking Peptide:For anti-TUBA1A (ARP84532_P050) antibody is Catalog # AAP84532Datasheets/Manuals:Printable datasheet for anti-TUBA1A (ARP84532_P050) antibody 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
