Echelon’sAutotaxinenzymeisasecretedhumanβisoform(teratocarcinomaderived)ofautotaxinwithC-terminal6-Histag
Storage:Storeproduct>-20ºC.Enzymeisstableforatleast6monthsat-20ºCasundilutedstockSpecificActivity:requestCertificateofAnalysis(COA)
ProductDescription
Thesecretedhumanβisoform(teratocarcinomaderived)autotaxinwithC-terminal6-HistagwasexpressedinSf9cellsandpurifiedusingnickel-NTAchromatography.Theenzymeissuppliedlyophilized(Containsdextrose,Hepes,trehaloseandTween20)andistestedforactivitybeforerelease.
Autotaxin,alsoknownasATX,eENPP2,lysophospholipaseD,phosphodiesterase1αandplasmacellglycoprotein-1,isasecretedglycoproteinthatiswidelyexpressedwithhighlevelsintheserum.ViaitslysophospholipaseD(lysoPLD)activityautotaxinhydrolyzeslysophosphatidylcholine(LPC)togeneratethephospholipidgrowthfactorlysophosphatidicacid(LPA).Theenzyme’ssameactivityhydrolyzessphingosylphosphorylcholine(SPC)toformsphinosine1-phosphate(S1P).
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TechnicalDataSheet
| Categories | Antibodies&Proteins |
|---|---|
| Filter | Autotaxin,Enzyme,Lipase |
