Gene Symbol:YWHABNCBI Gene Id:56011Protein Name:14-3-3 protein beta/alphaSwissprot Id:P35213Protein Accession #:NP_062250.1Replacement Item:This antibody may replace item sc-133232 from Santa Cruz Biotechnology.Description of Target:14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004; Dougherty and Morrison, 2004). The 14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking.Molecular Weight:~29kDaHost:RabbitClonality:PolyclonalPurification:Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the N-terminal peptide used as antigen.Application:WBTissue Tool:Find tissues and cell lines supported by DNA array analysis to express YWHAB. 
RNA Seq:Find tissues and cell lines supported by DNA array analysis to express YWHAB. 
Immunogen:Peptide corresponding to amino acid residues from the N-terminal region of the rat 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH).Predicted Species Reactivity:Cow, Dog, Human, Mouse, Rat, ZebrafishPredicted Homology Based on Immunogen Sequence:Cow; Dog; Human; Mouse; Rat; ZebrafishProduct Format:Liquid. 100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.Reconstitution and Storage:Store at -20C; stable for at least one year.Datasheets/Manuals:Printable datasheet for OAPC00020Specificity:Specific for the ~29k 14-3-3 protein. Immunolabeling of the 14-3-3 protein band is completely blocked by pre-adsorption of the antibody with the peptide that was used to generate the antibody. 我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
