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avivasysbio/EPHA2 Antibody (Phospho-Tyr588/596) (OASG02481)/100 uL/OASG02481

价格
¥4300.00
货号:OASG02481
浏览量:50
品牌:avivasysbio
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商品描述
Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IF
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-10746 from Santa Cruz Biotechnology.
Immunogen:
Synthesized peptide derived from human EphA2/3/4 around the phosphorylation site of Y588/596. Location: 530-610aa.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-EPHA2 (OASG02481) antibody
Target Post-Translational Modification:
Phospho-Tyr588/596
Specificity:
Phospho-EphA2/3/4 (Tyr588/596) Polyclonal Antibody detects endogenous levels of EphA2/3/4 protein only when phosphorylated at Y588/596.
Application Info:
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000;
Official Gene Full Name:
EPH receptor A2
Target:
EPHA2, EPHA3, EPHA4
Alias Symbols:
EPHA2, ECK, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human embryo kinase, Tyrosine-protein kinase TYRO
NCBI Gene Id:
1969; 2042; 2043; 13836; 13838; 29210
Description of Target:
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.
Swissprot Id:
P29317, P29320, P54764, Q03145, P29319, Q03137, O08680
Molecular Weight:
130 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express EPHA2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express EPHA2.
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。