Predicted Species Reactivity:HumanProduct Format:Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Clonality:PolyclonalHost:GoatReconstitution and Storage:Aliquot and store at -20C. Minimize freezing and thawing.Replacement Item:This antibody may replace item sc-367480 from Santa Cruz Biotechnology.Immunogen:This antibody is expected to recognize all reported Y-linked isoforms (NP_116753.1; NP_116754.1; NP_116755.1) and all reported X-linked isoforms (NP_055337.1; NP_055337.1; NP_116750.1; NP_116751.1).Predicted Homology Based on Immunogen Sequence:Human: 100%Complete computational species homology data:PCDH11Y Antibody (OAEB00765)Peptide Sequence:C-KYNWVTTPTTFKDatasheets/Manuals:Printable datasheet for anti-PCDH11Y antibody - OAEB00765Purity:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.Application Info:Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot: Preliminary experiments gave an approx 75kDa band in Human Brain (Amygdala, Hippocampus, Substantia nigra) lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 115kDa according to NP_116753.1 and of 113kDa according to NP_055337.1, the smallest reported isoforms. The 75kDa band was successfully blocked by incubation with the immunizing peptide.Target Reference:* Kalmady SV, Venkatasubramanian G,; Evidence for positive selection on Protocadherin Y gene in Homo sapiens: implications for schizophrenia.; Schizophrenia research 2009 Mar 108 (1-3): 299-300.; Pubmed 18938061Gene Symbol:PCDH11YAlias Symbols:PCDH11Y, protocadherin 11 Y-linked, PCDH-PC, PCDH11X, PCDH22, PCDHY, OTTHUMP00000033077, protocadherin 11 X-linked, protocadherin 22, protocadherin Y, RP13-138P15.1, PCDH-X, PCDH11, PCDHX, protocadherin 11X, protocadherin X, protocadherin-NCBI Gene Id:83259Protein Name:Protocadherin EMBL CAD92427.1Swissprot Id:Q6KER0Protein Accession #:NP_116753.1Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express PCDH11Y. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express PCDH11Y. 
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物,这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌,哺乳动物细胞和昆虫细胞中表达,并作为整体裂解物提供。