Gene Symbol:HDAC4Alias Symbols:HD4, AHO3, BDMR, HDACA, HA6116, HDAC-A, KIAA0288, HDAC-4NCBI Gene Id:9759Protein Name:Histone deacetylase 4Swissprot Id:P56524Protein Accession #:NP_006028Nucleotide Accession #:NM_006037Description of Target:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. Molecular Weight:40 Tissue Tool:Find tissues and cell lines supported by DNA array analysis to express HDAC4. 
RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express HDAC4. 
我们在Aviva Systems Biology生产并提供含有重组蛋白或天然蛋白的裂解物，这些蛋白可在Western blot检测中用作阳性对照。重组蛋白在细菌，哺乳动物细胞和昆虫细胞中表达，并作为整体裂解物提供。
